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Protocol for the BONE-RECON trial: a single-arm feasibility trial for critical sized lower limb BONE defect RECONstruction using the mPCL-TCP scaffold system with autologous vascularised corticoperiosteal tissue transfer

INTRODUCTION: Reconstruction of critical bone defects is challenging. In a substantial subgroup of patients, conventional reconstructive techniques are insufficient. Biodegradable scaffolds have emerged as a novel tissue engineering strategy for critical-sized bone defect reconstruction. A corticope...

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Detalles Bibliográficos
Autores principales: Sparks, David S, Wiper, Jay, Lloyd, Thomas, Wille, Marie-Luise, Sehu, Marjoree, Savi, Flavia M, Ward, Nicola, Hutmacher, Dietmar W, Wagels, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163528/
https://www.ncbi.nlm.nih.gov/pubmed/37137563
http://dx.doi.org/10.1136/bmjopen-2021-056440