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Glomerular mTORC1 activation was associated with podocytes to endothelial cells communication in lupus nephritis

OBJECTIVE: This study was initiated to evaluate the mammalian target of the rapamycin (mTOR) signalling pathway involved in renal endothelial-podocyte crosstalk in patients with lupus nephritis (LN). METHODS: We compared the kidney protein expression patterns of 10 patients with LN with severe endot...

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Detalles Bibliográficos
Autores principales: Liu, Xiaotian, Mao, Zhaomin, Yuan, Mo, Li, Linlin, Tan, Ying, Qu, Zhen, Chen, Min, Yu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163597/
https://www.ncbi.nlm.nih.gov/pubmed/37147021
http://dx.doi.org/10.1136/lupus-2023-000896