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Circ_0002984 promotes proliferation, migration and inflammatory cytokine secretion and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes by inducing PCSK6 through miR-543

BACKGROUND: Rheumatoid arthritis (RA) is inflammatory arthritic disease, and circular RNA is involved in RA development. The aim of the present work is to analyze the role of circ_0002984 in the process of RA fibroblast-like synoviocytes (RAFLSs) and the underlying mechanism. METHODS: Circ_0002984,...

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Detalles Bibliográficos
Autores principales: Lu, Jian-zuo, Yang, Jie, Zhou, Sheng-tuo, Xie, Kai-luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163683/
https://www.ncbi.nlm.nih.gov/pubmed/37149637
http://dx.doi.org/10.1186/s13018-023-03823-4