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DeepAR: a novel deep learning-based hybrid framework for the interpretable prediction of androgen receptor antagonists

Drug resistance represents a major obstacle to therapeutic innovations and is a prevalent feature in prostate cancer (PCa). Androgen receptors (ARs) are the hallmark therapeutic target for prostate cancer modulation and AR antagonists have achieved great success. However, rapid emergence of resistan...

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Detalles Bibliográficos
Autores principales: Schaduangrat, Nalini, Anuwongcharoen, Nuttapat, Charoenkwan, Phasit, Shoombuatong, Watshara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163717/
https://www.ncbi.nlm.nih.gov/pubmed/37149650
http://dx.doi.org/10.1186/s13321-023-00721-z