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DeepAR: a novel deep learning-based hybrid framework for the interpretable prediction of androgen receptor antagonists
Drug resistance represents a major obstacle to therapeutic innovations and is a prevalent feature in prostate cancer (PCa). Androgen receptors (ARs) are the hallmark therapeutic target for prostate cancer modulation and AR antagonists have achieved great success. However, rapid emergence of resistan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163717/ https://www.ncbi.nlm.nih.gov/pubmed/37149650 http://dx.doi.org/10.1186/s13321-023-00721-z |