Benefits of applying molecular barcoding systems are not uniform across different genomic applications

BACKGROUND: Despite the wide variety of Next Generation Sequencing (NGS)-based methods, it remains challenging to detect mutations present at very low frequencies. This problem is particularly relevant in oncology, where the limiting amount of input material, and its low quality, often limit the per...

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Detalles Bibliográficos
Autores principales: Bieler, Jonathan, Kubik, Slawomir, Macheret, Morgane, Pozzorini, Christian, Willig, Adrian, Xu, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163729/
https://www.ncbi.nlm.nih.gov/pubmed/37147717
http://dx.doi.org/10.1186/s12967-023-04160-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163729/
https://www.ncbi.nlm.nih.gov/pubmed/37147717
http://dx.doi.org/10.1186/s12967-023-04160-0

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