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Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice

BACKGROUND: Frontotemporal dementia (FTD) is a heterogeneous group of early onset and progressive neurodegenerative disorders, characterized by degeneration in the frontal and temporal lobes, which causes deterioration in cognition, personality, social behavior and language. Around 45% of the cases...

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Detalles Bibliográficos
Autores principales: Santos-García, Irene, Rodríguez-Cueto, Carmen, Villegas, Patricia, Piscitelli, Fabiana, Lauritano, Anna, Shen, Che-Kun J., Di Marzo, Vincenzo, Fernández-Ruiz, Javier, de Lago, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163746/
https://www.ncbi.nlm.nih.gov/pubmed/37149645
http://dx.doi.org/10.1186/s12974-023-02792-z