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Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice
BACKGROUND: Frontotemporal dementia (FTD) is a heterogeneous group of early onset and progressive neurodegenerative disorders, characterized by degeneration in the frontal and temporal lobes, which causes deterioration in cognition, personality, social behavior and language. Around 45% of the cases...
Autores principales: | Santos-García, Irene, Rodríguez-Cueto, Carmen, Villegas, Patricia, Piscitelli, Fabiana, Lauritano, Anna, Shen, Che-Kun J., Di Marzo, Vincenzo, Fernández-Ruiz, Javier, de Lago, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163746/ https://www.ncbi.nlm.nih.gov/pubmed/37149645 http://dx.doi.org/10.1186/s12974-023-02792-z |
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