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BK channel modulation by positively charged peptides and auxiliary γ subunits mediated by the Ca(2+)-bowl site
The large-conductance, Ca(2+)-, and voltage-activated K(+) (BK) channel consists of the pore-forming α (BKα) subunit and regulatory β and γ subunits. The γ1–3 subunits facilitate BK channel activation by shifting the voltage-dependence of channel activation toward the hyperpolarization direction by...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163825/ https://www.ncbi.nlm.nih.gov/pubmed/37130264 http://dx.doi.org/10.1085/jgp.202213237 |