Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment

Cancer metastasis to the brain is a significant clinical problem. Metastasis is the consequence of favorable interactions between invaded cancer cells and the microenvironment. Here, we demonstrate that cancer-activated astrocytes create a sustained low-level activated type I interferon (IFN) microe...

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Detalles Bibliográficos
Autores principales: Ma, Weili, Oliveira-Nunes, Maria Cecília, Xu, Ke, Kossenkov, Andrew, Reiner, Benjamin C., Crist, Richard C., Hayden, James, Chen, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163863/
https://www.ncbi.nlm.nih.gov/pubmed/37149684
http://dx.doi.org/10.1038/s41467-023-38252-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163863/
https://www.ncbi.nlm.nih.gov/pubmed/37149684
http://dx.doi.org/10.1038/s41467-023-38252-8

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