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Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment
Cancer metastasis to the brain is a significant clinical problem. Metastasis is the consequence of favorable interactions between invaded cancer cells and the microenvironment. Here, we demonstrate that cancer-activated astrocytes create a sustained low-level activated type I interferon (IFN) microe...
Autores principales: | Ma, Weili, Oliveira-Nunes, Maria Cecília, Xu, Ke, Kossenkov, Andrew, Reiner, Benjamin C., Crist, Richard C., Hayden, James, Chen, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163863/ https://www.ncbi.nlm.nih.gov/pubmed/37149684 http://dx.doi.org/10.1038/s41467-023-38252-8 |
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