N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness

Despite the advent of precision medicine and immunotherapy, mortality due to lung cancer remains high. The sonic hedgehog (SHH) cascade and its key terminal factor, glioma-associated oncogene homolog 1 (GLI1), play a pivotal role in the stemness and drug resistance of lung cancer. Here, we investiga...

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Detalles Bibliográficos
Autores principales: Dong, Hongliang, Zeng, Lili, Chen, Weiwei, Zhang, Qian, Wang, Fei, Wu, Yan, Cui, Bingjie, Qi, Jingjing, Zhang, Xin, Liu, Cuilan, Deng, Jiong, Yu, Yong, Schmitt, Clemens A., Du, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164154/
https://www.ncbi.nlm.nih.gov/pubmed/37149646
http://dx.doi.org/10.1038/s41420-023-01442-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164154/
https://www.ncbi.nlm.nih.gov/pubmed/37149646
http://dx.doi.org/10.1038/s41420-023-01442-w

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