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Mitochondrial citrate metabolism and efflux regulate BeWo differentiation

Cytotrophoblasts fuse to form and renew syncytiotrophoblasts necessary to maintain placental health throughout gestation. During cytotrophoblast to syncytiotrophoblast differentiation, cells undergo regulated metabolic and transcriptional reprogramming. Mitochondria play a critical role in different...

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Detalles Bibliográficos
Autores principales: Mahr, Renee M., Jena, Snehalata, Nashif, Sereen K., Nelson, Alisa B., Rauckhorst, Adam J., Rome, Ferrol I., Sheldon, Ryan D., Hughey, Curtis C., Puchalska, Patrycja, Gearhart, Micah D., Taylor, Eric B., Crawford, Peter A., Wernimont, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164164/
https://www.ncbi.nlm.nih.gov/pubmed/37149697
http://dx.doi.org/10.1038/s41598-023-34435-x