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Evaluation of multigene assays as predictors for response to neoadjuvant chemotherapy in early-stage breast cancer patients

OncotypeDX and MammaPrint assays have not been validated to predict pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) in early-stage breast cancer patients. We analyzed the 2010–2019 National Cancer Database and found that high OncotypeDX recurrence scores or high MammaPrint scor...

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Detalles Bibliográficos
Autores principales: Freeman, Jincong Q., Shubeck, Sarah, Howard, Frederick M., Chen, Nan, Nanda, Rita, Huo, Dezheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164191/
https://www.ncbi.nlm.nih.gov/pubmed/37149628
http://dx.doi.org/10.1038/s41523-023-00536-z