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C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors

The skin is the first line of defense to cutaneous microbes and viruses, and epidermal keratinocytes play a critical role in preventing infection by viruses and pathogens through activation of the type I interferon (IFN) response. Using RNAseq analysis, here we report that the conditional deletion o...

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Detalles Bibliográficos
Autores principales: House, John S., Gray, Sophia, Owen, Jennifer R., Jima, Dereje D., Smart, Robert C., Hall, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164275/
https://www.ncbi.nlm.nih.gov/pubmed/37094088
http://dx.doi.org/10.1177/17534259231162192