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MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia

BACKGROUND: The previous studies have revealed that abnormal RNA-binding protein Musashi-2 (MSI2) expression is associated with cancer progression through post-transcriptional mechanisms, however mechanistic details of this regulation in acute myeloid leukemia (AML) still remain unclear. Our study a...

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Detalles Bibliográficos
Autores principales: Li, Fanfan, Han, Yixiang, Chen, Rongrong, Jiang, Yinyan, Chen, Cheng, Wang, Xiaofang, Zhou, Jifan, Xu, Qingqing, Jiang, Songfu, Zhang, Si, Yu, Kang, Zhang, Shenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164318/
https://www.ncbi.nlm.nih.gov/pubmed/37149661
http://dx.doi.org/10.1186/s12967-023-04106-6