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Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma

We used pyroptosis-related genes to establish a risk–score model for prognostic prediction of liver hepatocellular carcinoma (LIHC) patients. A total of 52 pyroptosis-associated genes were identified. Then, data for 374 LIHC patients and 50 normal individuals were acquired from the TCGA database. Th...

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Detalles Bibliográficos
Autores principales: Chen, Xinyi, Yang, Mu, Wang, Lu, Wang, Yuan, Tu, Jingyao, Zhou, Xiao, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164321/
https://www.ncbi.nlm.nih.gov/pubmed/37149620
http://dx.doi.org/10.1186/s12885-023-10850-1