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Model-based assessment of combination therapies – ranking of radiosensitizing agents in oncology

BACKGROUND: To increase the chances of finding efficacious anticancer drugs, improve development times and reduce costs, it is of interest to rank test compounds based on their potential for human use as early as possible in the drug development process. In this paper, we present a method for rankin...

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Detalles Bibliográficos
Autores principales: Baaz, Marcus, Cardilin, Tim, Lignet, Floriane, Zimmermann, Astrid, El Bawab, Samer, Gabrielsson, Johan, Jirstrand, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164338/
https://www.ncbi.nlm.nih.gov/pubmed/37149596
http://dx.doi.org/10.1186/s12885-023-10899-y