FAM193A is a positive regulator of p53 activity

Inactivation of the p53 tumor suppressor, either by mutations or through hyperactivation of repressors such as MDM2 and MDM4, is a hallmark of cancer. Although many inhibitors of the p53-MDM2/4 interaction have been developed, such as Nutlin, their therapeutic value is limited by highly heterogeneou...

Descripción completa

Detalles Bibliográficos
Autores principales: Szwarc, Maria M., Guarnieri, Anna L., Joshi, Molishree, Duc, Huy N., Laird, Madison C., Pandey, Ahwan, Khanal, Santosh, Dohm, Emily, Bui, Aimee K., Sullivan, Kelly D., Galbraith, Matthew D., Andrysik, Zdenek, Espinosa, Joaquin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164416/
https://www.ncbi.nlm.nih.gov/pubmed/36897777
http://dx.doi.org/10.1016/j.celrep.2023.112230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164416/
https://www.ncbi.nlm.nih.gov/pubmed/36897777
http://dx.doi.org/10.1016/j.celrep.2023.112230

Ejemplares similares