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7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system

The modified nucleosides 2′-deoxy-7-cyano- and 2′-deoxy-7-amido-7-deazaguanosine (dPreQ(0) and dADG, respectively) recently discovered in DNA are the products of the bacterial queuosine tRNA modification pathway and the dpd gene cluster, the latter of which encodes proteins that comprise the elabora...

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Detalles Bibliográficos
Autores principales: Gedara, Samanthi Herath, Wood, Evan, Gustafson, Andrew, Liang, Cui, Hung, Shr-Hau, Savage, Joshua, Phan, Phuc, Luthra, Amit, de Crécy-Lagard, Valérie, Dedon, Peter, Swairjo, Manal A, Iwata-Reuyl, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164549/
https://www.ncbi.nlm.nih.gov/pubmed/36928176
http://dx.doi.org/10.1093/nar/gkad141