PBRM1 bromodomains associate with RNA to facilitate chromatin association

PBRM1 is a subunit of the PBAF chromatin remodeling complex, which is mutated in 40–50% of clear cell renal cell carcinoma patients. It is thought to largely function as a chromatin binding subunit of the PBAF complex, but the molecular mechanism underlying this activity is not fully known. PBRM1 co...

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Detalles Bibliográficos
Autores principales: De Silva, Saumya M, Dhiman, Alisha, Sood, Surbhi, Mercedes, Kilsia F, Simmons, William J, Henen, Morkos A, Vögeli, Beat, Dykhuizen, Emily C, Musselman, Catherine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164552/
https://www.ncbi.nlm.nih.gov/pubmed/36808431
http://dx.doi.org/10.1093/nar/gkad072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164552/
https://www.ncbi.nlm.nih.gov/pubmed/36808431
http://dx.doi.org/10.1093/nar/gkad072

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