Genomic targets of the IRE1-XBP1s pathway in mediating metabolic adaptation in epithelial plasticity

Epithelial mesenchymal plasticity (EMP) is a complex cellular reprogramming event that plays a major role in tissue homeostasis. Recently we observed the unfolded protein response (UPR) triggers EMP through the inositol-requiring protein 1 (IRE1α)–X-box-binding protein 1 spliced (XBP1s) axis, enhanc...

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Detalles Bibliográficos
Autores principales: Qiao, Dianhua, Skibba, Melissa, Xu, Xiaofang, Brasier, Allan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164557/
https://www.ncbi.nlm.nih.gov/pubmed/36772828
http://dx.doi.org/10.1093/nar/gkad077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164557/
https://www.ncbi.nlm.nih.gov/pubmed/36772828
http://dx.doi.org/10.1093/nar/gkad077

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