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Genomic targets of the IRE1-XBP1s pathway in mediating metabolic adaptation in epithelial plasticity
Epithelial mesenchymal plasticity (EMP) is a complex cellular reprogramming event that plays a major role in tissue homeostasis. Recently we observed the unfolded protein response (UPR) triggers EMP through the inositol-requiring protein 1 (IRE1α)–X-box-binding protein 1 spliced (XBP1s) axis, enhanc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164557/ https://www.ncbi.nlm.nih.gov/pubmed/36772828 http://dx.doi.org/10.1093/nar/gkad077 |