Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase

The N-(2-deoxy-d-erythro-pentofuranosyl)-urea DNA lesion forms following hydrolytic fragmentation of cis-5R,6S- and trans-5R,6R-dihydroxy-5,6-dihydrothymidine (thymine glycol, Tg) or from oxidation of 7,8-dihydro-8-oxo-deoxyguanosine (8-oxodG) and subsequent hydrolysis. It interconverts between α an...

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Detalles Bibliográficos
Autores principales: Tomar, Rachana, Minko, Irina G, Sharma, Pankaj, Kellum, Andrew H, Lei, Li, Harp, Joel M, Iverson, T M, Lloyd, R Stephen, Egli, Martin, Stone, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164570/
https://www.ncbi.nlm.nih.gov/pubmed/37014002
http://dx.doi.org/10.1093/nar/gkad164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164570/
https://www.ncbi.nlm.nih.gov/pubmed/37014002
http://dx.doi.org/10.1093/nar/gkad164

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