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CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
During every cell cycle, both the genome and the associated chromatin must be accurately replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication, but how CAF-1 functions in relation to the DNA replication machinery is unknown. Here, we reveal that this crosstalk d...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164577/ https://www.ncbi.nlm.nih.gov/pubmed/36942484 http://dx.doi.org/10.1093/nar/gkad171 |