CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands

During every cell cycle, both the genome and the associated chromatin must be accurately replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication, but how CAF-1 functions in relation to the DNA replication machinery is unknown. Here, we reveal that this crosstalk d...

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Detalles Bibliográficos
Autores principales: Rouillon, Clément, Eckhardt, Bruna V, Kollenstart, Leonie, Gruss, Fabian, Verkennis, Alexander E E, Rondeel, Inge, Krijger, Peter H L, Ricci, Giulia, Biran, Alva, van Laar, Theo, Delvaux de Fenffe, Charlotte M, Luppens, Georgiana, Albanese, Pascal, Sato, Koichi, Scheltema, Richard A, de Laat, Wouter, Knipscheer, Puck, Dekker, Nynke H, Groth, Anja, Mattiroli, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164577/
https://www.ncbi.nlm.nih.gov/pubmed/36942484
http://dx.doi.org/10.1093/nar/gkad171

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