Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects

Combination cancer chemotherapy is one of the most useful treatment methods to achieve a synergistic effect and reduce the toxicity of dosing with a single drug. Here, we use a combination of two well-established anticancer DNA intercalators, actinomycin D (ActD) and echinomycin (Echi), to screen th...

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Detalles Bibliográficos
Autores principales: Satange, Roshan, Chang, Chih-Chun, Li, Long‐Yuan, Lin, Sheng-Hao, Neidle, Stephen, Hou, Ming-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164580/
https://www.ncbi.nlm.nih.gov/pubmed/36919604
http://dx.doi.org/10.1093/nar/gkad156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164580/
https://www.ncbi.nlm.nih.gov/pubmed/36919604
http://dx.doi.org/10.1093/nar/gkad156

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