Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans

O-Phosphoseryl-tRNA(Sec) selenium transferase (SepSecS) catalyzes the terminal step of selenocysteine (Sec) synthesis in archaea and eukaryotes. How the Sec synthetic machinery recognizes and discriminates tRNA(Sec) from the tRNA pool is essential to the integrity of the selenoproteome. Previously,...

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Detalles Bibliográficos
Autores principales: Puppala, Anupama K, Castillo Suchkou, Jennifer, French, Rachel L, Kiernan, Kaitlyn A, Simonović, Miljan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164584/
https://www.ncbi.nlm.nih.gov/pubmed/36929010
http://dx.doi.org/10.1093/nar/gkad182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164584/
https://www.ncbi.nlm.nih.gov/pubmed/36929010
http://dx.doi.org/10.1093/nar/gkad182

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