G-quadruplex-based CRISPR photoswitch for spatiotemporal control of genomic modulation

CRISPR (clustered regularly interspaced short palindromic repeats) technology holds tremendous promise for gene regulation and editing. However, precise control of CRISPR editing is essential to overcome its uncontrollable reaction process and excessive activity that leads to off-target editing. To...

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Detalles Bibliográficos
Autores principales: Deng, Huaping, Xu, Han, Wang, Yiru, Jia, Ruizhen, Ma, Xiaoqian, Feng, Yushuo, Chen, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164585/
https://www.ncbi.nlm.nih.gov/pubmed/36912089
http://dx.doi.org/10.1093/nar/gkad178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164585/
https://www.ncbi.nlm.nih.gov/pubmed/36912089
http://dx.doi.org/10.1093/nar/gkad178

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