Cargando…

G-quadruplex-based CRISPR photoswitch for spatiotemporal control of genomic modulation

CRISPR (clustered regularly interspaced short palindromic repeats) technology holds tremendous promise for gene regulation and editing. However, precise control of CRISPR editing is essential to overcome its uncontrollable reaction process and excessive activity that leads to off-target editing. To...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Huaping, Xu, Han, Wang, Yiru, Jia, Ruizhen, Ma, Xiaoqian, Feng, Yushuo, Chen, Hongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164585/ https://www.ncbi.nlm.nih.gov/pubmed/36912089 http://dx.doi.org/10.1093/nar/gkad178

Ejemplares similares

G-quadruplex-guided RNA engineering to modulate CRISPR-based genomic regulation
por: Liu, Xingyu, et al.
Publicado: (2022)

CRISPR–Cas12a system in fission yeast for multiplex genomic editing and CRISPR interference
por: Zhao, Yu, et al.
Publicado: (2020)

An in-library ligation strategy and its application in CRISPR/Cas9 screening of high-order gRNA combinations
por: Lu, Zhike, et al.
Publicado: (2022)

Streamlined CRISPR genome engineering in wild-type bacteria using SIBR-Cas
por: Patinios, Constantinos, et al.
Publicado: (2021)

Repurposing CRISPR RNA-guided integrases system for one-step, efficient genomic integration of ultra-long DNA sequences
por: Cheng, Zhou-Hua, et al.
Publicado: (2022)

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR–Cas12a gRNA switch
por: Collins, Scott P, et al.
Publicado: (2021)

Characterization and repurposing of the endogenous Type I-F CRISPR–Cas system of Zymomonas mobilis for genome engineering
por: Zheng, Yanli, et al.
Publicado: (2019)

Activating cryptic biosynthetic gene cluster through a CRISPR–Cas12a-mediated direct cloning approach
por: Liang, Mindong, et al.
Publicado: (2022)

Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking
por: Chen, Xiaoyu, et al.
Publicado: (2020)

Establishing artificial gene connections through RNA displacement–assembly-controlled CRISPR/Cas9 function
por: Wang, Wei-Jia, et al.
Publicado: (2023)

A functional type II-A CRISPR–Cas system from Listeria enables efficient genome editing of large non-integrating bacteriophage
por: Hupfeld, Mario, et al.
Publicado: (2018)

Orthogonal CRISPR-associated transposases for parallel and multiplexed chromosomal integration
por: Yang, Siqi, et al.
Publicado: (2021)

Unmodificated stepless regulation of CRISPR/Cas12a multi-performance
por: Zhao, Rong, et al.
Publicado: (2023)

Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells
por: Tasca, Francesca, et al.
Publicado: (2022)

CRISPR-based self-cleaving mechanism for controllable gene delivery in human cells
por: Moore, Richard, et al.
Publicado: (2015)

Programmable control of bacterial gene expression with the combined CRISPR and antisense RNA system
por: Lee, Young Je, et al.
Publicado: (2016)

Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
por: Luo, Michelle L., et al.
Publicado: (2015)

Activating natural product synthesis using CRISPR interference and activation systems in Streptomyces
por: Ameruoso, Andrea, et al.
Publicado: (2022)

A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeast
por: Hofmann, Anja, et al.
Publicado: (2019)

Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing
por: Shin, Ha Rim, et al.
Publicado: (2021)

Toward a translationally independent RNA-based synthetic oscillator using deactivated CRISPR-Cas
por: Kuo, James, et al.
Publicado: (2020)

Rational guide RNA engineering for small-molecule control of CRISPR/Cas9 and gene editing
por: Liu, Xingyu, et al.
Publicado: (2022)

Imperfect guide-RNA (igRNA) enables CRISPR single-base editing with ABE and CBE
por: Zhao, Dongdong, et al.
Publicado: (2022)

Rational engineering of a modular bacterial CRISPR–Cas activation platform with expanded target range
por: Villegas Kcam, Maria Claudia, et al.
Publicado: (2021)

Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters
por: Rossetti, Marianna, et al.
Publicado: (2022)

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis
por: Mason, Derek M, et al.
Publicado: (2018)

Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA
por: Shebanova, Regina, et al.
Publicado: (2021)

CRISPR-mediated protein-tagging signal amplification systems for efficient transcriptional activation and repression in Saccharomyces cerevisiae
por: Zhai, Haotian, et al.
Publicado: (2022)

CRISPR-RNAa: targeted activation of translation using dCas13 fusions to translation initiation factors
por: Otoupal, Peter B, et al.
Publicado: (2022)

Targeted-antibacterial-plasmids (TAPs) combining conjugation and CRISPR/Cas systems achieve strain-specific antibacterial activity
por: Reuter, Audrey, et al.
Publicado: (2021)

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus
por: Aulicino, Francesco, et al.
Publicado: (2022)

Photoswitchable gRNAs for Spatiotemporally Controlled CRISPR-Cas-Based Genomic Regulation
por: Moroz-Omori, Elena V., et al.
Publicado: (2020)

MiniCAFE, a CRISPR/Cas9-based compact and potent transcriptional activator, elicits gene expression in vivo
por: Zhang, Xin, et al.
Publicado: (2021)

Spacer2PAM: A computational framework to guide experimental determination of functional CRISPR-Cas system PAM sequences
por: Rybnicky, Grant A, et al.
Publicado: (2022)

CRISPR-associated type V proteins as a tool for controlling mRNA stability in S. cerevisiae synthetic gene circuits
por: Yu, Lifang, et al.
Publicado: (2023)

How long is too long? Effects of loop size on G-quadruplex stability
por: Guédin, Aurore, et al.
Publicado: (2010)

Multiplexed activation in mammalian cells using a split-intein CRISPR/Cas12a based synthetic transcription factor
por: Bryson, James W, et al.
Publicado: (2021)

Repurposing the atypical type I-G CRISPR system for bacterial genome engineering
por: Shangguan, Qilin, et al.
Publicado: (2023)

Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription
por: Xie, Jingke, et al.
Publicado: (2023)

Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification
por: Haldrup, Jakob, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8u3fbp2t4r50qq2fmmmhkkvlgm