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Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP

While TXNIP (thioredoxin interacting protein) in the plasma membrane and vesicular location is known to negatively regulate cellular glucose uptake by facilitating glucose transporter endocytosis, the function of TXNIP in the nucleus is far less understood. Herein, we sought to determine the functio...

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Detalles Bibliográficos
Autores principales: Waldhart, Althea N., Lau, Kin H., Dykstra, Holly, Avequin, Tracey, Wu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164894/
https://www.ncbi.nlm.nih.gov/pubmed/37168572
http://dx.doi.org/10.1016/j.isci.2023.106538