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Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP

Salmonella Typhimurium drives uptake into non-phagocytic host cells by injecting effector proteins that reorganize the actin cytoskeleton. The host actin regulator N-WASP has been implicated in bacterial entry, but its precise role is not clear. We demonstrate that Cdc42-dependent N-WASP activation,...

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Detalles Bibliográficos
Autores principales: Davidson, Anthony, Hume, Peter J., Greene, Nicholas P., Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164908/
https://www.ncbi.nlm.nih.gov/pubmed/37168569
http://dx.doi.org/10.1016/j.isci.2023.106643