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The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation
The Somatostatin receptor 2 (Sstr2) is a heterotrimeric G protein-coupled receptor that is highly expressed in neuroendocrine tumors and is a common pharmacological target for intervention. Unfortunately, not all neuroendocrine tumors express Sstr2, and Sstr2 expression can be downregulated with pro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164914/ https://www.ncbi.nlm.nih.gov/pubmed/36965619 http://dx.doi.org/10.1016/j.jbc.2023.104645 |