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Buspirone Induces Weight Loss and Normalization of Blood Pressure via the Stimulation of PPARδ Dependent Energy Producing Pathway in Spontaneously Hypertensive Rats

INTRODUCTION: Buspirone, as a partial agonist for a 5-hydroxytryptamine (serotonin) receptor 1A (5-HT1A), has been prescribed as an anxiolytic drug for patients. In addition, the lowering effect of serotonin on blood pressure was reported in hypertensive animal model. We investigated the therapeutic...

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Detalles Bibliográficos
Autores principales: Lee, Yong-Jik, Kim, Hyun-Min, Jang, Yoo-Na, Han, Yoon-Mi, Seo, Hong Seog, Jung, Tae Woo, Jeong, Ji Hoon, Lee, Hyun Jung, Jung, Kyung Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164918/
https://www.ncbi.nlm.nih.gov/pubmed/37168052
http://dx.doi.org/10.1155/2023/7550164