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Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zinc

Zinc is an important component of cellular antioxidant defenses and dysregulation of zinc homeostasis is a risk factor for coronary heart disease and ischemia/reperfusion injury. Intracellular homeostasis of metals, such as zinc, iron and calcium are interrelated with cellular responses to oxidative...

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Detalles Bibliográficos
Autores principales: Smith, Matthew J., Yang, Fan, Griffiths, Alexander, Morrell, Alexander, Chapple, Sarah J., Siow, Richard C.M., Stewart, Theodora, Maret, Wolfgang, Mann, Giovanni E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165141/
https://www.ncbi.nlm.nih.gov/pubmed/37116256
http://dx.doi.org/10.1016/j.redox.2023.102712