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Antiviral activity of glucosylceramide synthase inhibitors in alphavirus infection of the central nervous system

Virus-induced CNS diseases impose a considerable human health burden worldwide. For many viral CNS infections, neither antiviral drugs nor vaccines are available. In this study, we examined whether the synthesis of glycosphingolipids, major membrane lipid constituents, could be used to establish an...

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Detalles Bibliográficos
Autores principales: Avraham, Roy, Melamed, Sharon, Achdout, Hagit, Erez, Noam, Israeli, Ofir, Barlev-Gross, Moria, Pasmanik-Chor, Metsada, Paran, Nir, Israely, Tomer, Vitner, Einat B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165247/
https://www.ncbi.nlm.nih.gov/pubmed/37168733
http://dx.doi.org/10.1093/braincomms/fcad086