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Antiviral activity of glucosylceramide synthase inhibitors in alphavirus infection of the central nervous system
Virus-induced CNS diseases impose a considerable human health burden worldwide. For many viral CNS infections, neither antiviral drugs nor vaccines are available. In this study, we examined whether the synthesis of glycosphingolipids, major membrane lipid constituents, could be used to establish an...
Autores principales: | Avraham, Roy, Melamed, Sharon, Achdout, Hagit, Erez, Noam, Israeli, Ofir, Barlev-Gross, Moria, Pasmanik-Chor, Metsada, Paran, Nir, Israely, Tomer, Vitner, Einat B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165247/ https://www.ncbi.nlm.nih.gov/pubmed/37168733 http://dx.doi.org/10.1093/braincomms/fcad086 |
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