Cargando…

TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination

Mitochondrial antiviral signaling (MAVS) protein is a core signaling adapter in the retinoid acid–inducible gene-I–like receptor (RLR) signaling pathway that recruits downstream signaling factors, ultimately leading to the activation of type Ⅰ interferons. However, the mechanisms that modulate the R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ya-Yun, Ran, Xiang-Hong, Ni, Run-Ze, Mu, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165269/ https://www.ncbi.nlm.nih.gov/pubmed/37119745 http://dx.doi.org/10.1016/j.jbc.2023.104660

Ejemplares similares

BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS
por: Huang, Jing-Ping, et al.
Publicado: (2022)

TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1
por: Huang, Jing-Ping, et al.
Publicado: (2023)

USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS
por: Hou, Jinxiu, et al.
Publicado: (2021)

Zika Virus Non-structural Protein 4A Blocks the RLR-MAVS Signaling
por: Ma, Jinzhu, et al.
Publicado: (2018)

Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling
por: Sui, Liyan, et al.
Publicado: (2023)

Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner
por: Ran, Xiang-Hong, et al.
Publicado: (2022)

Human Herpesvirus 6B U26 Inhibits the Activation of the RLR/MAVS Signaling Pathway
por: Jiang, Xuefeng, et al.
Publicado: (2021)

Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation
por: Lemma, Betsegaw, et al.
Publicado: (2023)

TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity
por: Wang, Xueer, et al.
Publicado: (2021)

TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination
por: Li, Wei, et al.
Publicado: (2019)

MARCH3 negatively regulates IL-3-triggered inflammatory response by mediating K48-linked polyubiquitination and degradation of IL-3Rα
por: Feng, Lu, et al.
Publicado: (2022)

RNF39 mediates K48-linked ubiquitination of DDX3X and inhibits RLR-dependent antiviral immunity
por: Wang, Wenwen, et al.
Publicado: (2021)

TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3
por: Wang, Peng, et al.
Publicado: (2015)

Methylcrotonoyl-CoA carboxylase 1 potentiates RLR-induced NF-κB signaling by targeting MAVS complex
por: Cao, Zhongying, et al.
Publicado: (2016)

BICP0 Negatively Regulates TRAF6-Mediated NF-κB and Interferon Activation by Promoting K48-Linked Polyubiquitination of TRAF6
por: Cao, Chong, et al.
Publicado: (2020)

TRIM15 and CYLD regulate ERK activation via lysine 63-linked polyubiquitination
por: Zhu, Guixin, et al.
Publicado: (2021)

Duck TRIM29 negatively regulates type I IFN production by targeting MAVS
por: Li, Weiqiang, et al.
Publicado: (2023)

Natural small molecule FMHM inhibits lipopolysaccharide-induced inflammatory response by promoting TRAF6 degradation via K48-linked polyubiquitination
por: Zeng, Ke-Wu, et al.
Publicado: (2015)

C-Cbl negatively regulates TRAF6-mediated NF-κB activation by promoting K48-linked polyubiquitination of TRAF6
por: Jang, Hyun-Duk, et al.
Publicado: (2019)

Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRα by K48/K63-linked polyubiquitination
por: Shi, Wen-Na, et al.
Publicado: (2017)

Large yellow croaker (Larimichthys crocea) mitofusin 2 inhibits type I IFN responses by degrading MAVS via enhanced K48-linked ubiquitination
por: Li, Wen-Xing, et al.
Publicado: (2023)

RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination
por: Yang, Ziwei, et al.
Publicado: (2021)

IRTKS negatively regulates antiviral immunity through PCBP2 sumoylation-mediated MAVS degradation
por: Xia, Pengyan, et al.
Publicado: (2015)

ZNF205 positively regulates RLR antiviral signaling by targeting RIG-I: ZNF205 regulates RLR antiviral signaling
por: Zhong, Ni, et al.
Publicado: (2023)

Correction: RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination
por: Yang, Ziwei, et al.
Publicado: (2021)

USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication
por: Xu, Chao, et al.
Publicado: (2018)

Endogenous Retroviruses (ERVs): Does RLR (RIG-I-Like Receptors)-MAVS Pathway Directly Control Senescence and Aging as a Consequence of ERV De-Repression?
por: Di Giorgio, Eros, et al.
Publicado: (2022)

The role of K63‐linked polyubiquitination in cardiac hypertrophy
por: Yan, Kaowen, et al.
Publicado: (2018)

Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains
por: Di Rienzo, M., et al.
Publicado: (2019)

Sex-differences in proteasome-dependent K48-polyubiquitin signaling in the amygdala are developmentally regulated in rats
por: Farrell, Kayla, et al.
Publicado: (2023)

Crosstalk between Autophagy and RLR Signaling
por: Ke, Po-Yuan
Publicado: (2023)

TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression
por: Fong, Ka-wing, et al.
Publicado: (2018)

TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO
por: Yu, Zhou, et al.
Publicado: (2021)

Author Correction: USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication
por: Xu, Chao, et al.
Publicado: (2023)

TRIM34 modulates influenza virus-activated programmed cell death by targeting Z-DNA-binding protein 1 for K63-linked polyubiquitination
por: Wang, Xiaoyan, et al.
Publicado: (2022)

GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome
por: Nie, Ying, et al.
Publicado: (2017)

TRIM5α recruits HDAC1 to p50 and Sp1 and promotes H3K9 deacetylation at the HIV-1 LTR
por: Ran, Xiang-Hong, et al.
Publicado: (2023)

Regulation of RIG-I Activation by K63-Linked Polyubiquitination
por: Okamoto, Masaaki, et al.
Publicado: (2018)

Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin
por: Michel, Martin A., et al.
Publicado: (2015)

The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5
por: Bu, Lang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d7nr43ltm0tfr1mmnia3rmiun3