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Mechanisms and efficacy of metformin-mediated suppression of established experimental abdominal aortic aneurysms

OBJECTIVE: Metformin treatment attenuates experimental abdominal aortic aneurysm (AAA) formation, as well as reduces clinical AAA diameter enlargement in patients with diabetes. The mechanisms of metformin-mediated aneurysm suppression, and its efficacy in suppressing established experimental aneury...

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Detalles Bibliográficos
Autores principales: Xu, Baohui, Li, Gang, Li, Yankui, Deng, Hongping, Cabot, Anna, Guo, Jia, Samura, Makoto, Zheng, Xiaoya, Chen, Tiffany, Zhao, Sihai, Fujimura, Naoki, Dalman, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165270/
https://www.ncbi.nlm.nih.gov/pubmed/37168662
http://dx.doi.org/10.1016/j.jvssci.2023.100102