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The PROB-PD trial: a pilot, randomised, placebo-controlled study protocol to evaluate the feasibility and potential efficacy of probiotics in modulating peripheral immunity in subjects with Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a common neurodegenerative disease. No disease-modifying treatment is available, and therapy is symptomatic. The histopathologic hallmark is the loss of dopaminergic neurons and accumulation of α-synuclein (α-syn) in surviving neurons, but the underlying patho...

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Detalles Bibliográficos
Autores principales: Martini, Stefano, Marino, Franca, Magistrelli, Luca, Contaldi, Elena, Cosentino, Marco, Comi, Cristoforo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165276/
https://www.ncbi.nlm.nih.gov/pubmed/37158925
http://dx.doi.org/10.1186/s40814-023-01306-1