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TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions

Protein ubiquitination is a post-translation modification mediated by E3 ubiquitin ligases. The RING domain E3 ligases are the largest family of E3 ubiquitin ligases, they act as a scaffold, bringing the E2-ubiquitin complex and its substrate together to facilitate direct ubiquitin transfer. However...

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Detalles Bibliográficos
Autores principales: Lou, Xiaohua, Ma, Binbin, Zhuang, Yuan, Xiao, Xiang, Minze, Laurie J., Xing, Junji, Zhang, Zhiqiang, Li, Xian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165346/
https://www.ncbi.nlm.nih.gov/pubmed/37168870
http://dx.doi.org/10.1016/j.csbj.2023.04.022