ASO targeting RBM3 temperature‐controlled poison exon splicing prevents neurodegeneration in vivo

Neurodegenerative diseases are increasingly prevalent in the aging population, yet no disease‐modifying treatments are currently available. Increasing the expression of the cold‐shock protein RBM3 through therapeutic hypothermia is remarkably neuroprotective. However, systemic cooling poses a health...

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Detalles Bibliográficos
Autores principales: Preußner, Marco, Smith, Heather L, Hughes, Daniel, Zhang, Min, Emmerichs, Ann‐Kathrin, Scalzitti, Silvia, Peretti, Diego, Swinden, Dean, Neumann, Alexander, Haltenhof, Tom, Mallucci, Giovanna R, Heyd, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165353/
https://www.ncbi.nlm.nih.gov/pubmed/36946385
http://dx.doi.org/10.15252/emmm.202217157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165353/
https://www.ncbi.nlm.nih.gov/pubmed/36946385
http://dx.doi.org/10.15252/emmm.202217157

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