OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

Effective depletion of immune suppressive regulatory T cells (Tregs) in the tumor microenvironment without triggering systemic autoimmunity is an important strategy for cancer immunotherapy. Modified vaccinia virus Ankara (MVA) is a highly attenuated, non-replicative vaccinia virus with a long histo...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Wang, Yi, Liu, Shuaitong, Tariq, Shanza Baseer, Luna, Joseph M., Mazo, Gregory, Tan, Adrian, Zhang, Tuo, Wang, Jiahu, Yan, Wei, Choi, John, Rossi, Anthony, Xiang, Jenny Zhaoying, Rice, Charles M., Merghoub, Taha, Wolchok, Jedd D., Deng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165539/
https://www.ncbi.nlm.nih.gov/pubmed/37145142
http://dx.doi.org/10.1084/jem.20221166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165539/
https://www.ncbi.nlm.nih.gov/pubmed/37145142
http://dx.doi.org/10.1084/jem.20221166

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