Features of CFTR mRNA and implications for therapeutics development

Cystic fibrosis (CF) is an autosomal recessive disease impacting ∼100,000 people worldwide. This lethal disorder is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene, which encodes an ATP-binding cassette-class C protein. More than 2,100 variants have been identified throu...

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Detalles Bibliográficos
Autores principales: Jackson, JaNise J., Mao, Yiyang, White, Tyshawn R., Foye, Catherine, Oliver, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165737/
https://www.ncbi.nlm.nih.gov/pubmed/37168508
http://dx.doi.org/10.3389/fgene.2023.1166529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165737/
https://www.ncbi.nlm.nih.gov/pubmed/37168508
http://dx.doi.org/10.3389/fgene.2023.1166529

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