Panax notoginseng saponins inhibits NLRP3 inflammasome-mediated pyroptosis by downregulating lncRNA-ANRIL in cardiorenal syndrome type 4

OBJECTIVE: Cardiorenal syndrome type 4 (CRS4) is a complication of chronic kidney disease. Panax notoginseng saponins (PNS) have been confirmed to be efficient in cardiovascular diseases. Our study aimed to explore the therapeutic role and mechanism of PNS in CRS4. METHODS: CRS4 model rats and hypox...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Cao, Luxi, Zou, Wenli, Yu, Rizhen, Shen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165771/
https://www.ncbi.nlm.nih.gov/pubmed/37158944
http://dx.doi.org/10.1186/s13020-023-00756-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165771/
https://www.ncbi.nlm.nih.gov/pubmed/37158944
http://dx.doi.org/10.1186/s13020-023-00756-2

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