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TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome

BACKGROUND: Ovarian hyperstimulation syndrome (OHSS) is a serious complication during in vitro fertilization (IVF) treatment. The upregulation of ovarian transforming growth factor-beta 1 (TGF-β1) is involved in the development of OHSS. The secreted protein acidic and rich in cysteine (SPARC) is a s...

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Detalles Bibliográficos
Autores principales: Dang, Xuan, Fang, Lanlan, Jia, Qiongqiong, Wu, Ze, Guo, Yanjie, Liu, Boqun, Cheng, Jung-Chien, Sun, Ying-Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165787/
https://www.ncbi.nlm.nih.gov/pubmed/37158892
http://dx.doi.org/10.1186/s12964-023-01123-2