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Selective inhibition of somatostatin-positive dentate hilar interneurons induces age-related cellular changes and cognitive dysfunction
The cellular basis of age-related impairments of hippocampal function is not fully understood. In order to evaluate the role of somatostatin-positive (Sst(+)) interneurons in the dentate gyrus (DG) hilus in this process, we chemogenetically inhibited Sst(+) interneurons in the DG hilus. Chronic chem...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165806/ https://www.ncbi.nlm.nih.gov/pubmed/37168673 http://dx.doi.org/10.1093/pnasnexus/pgad134 |