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Targeting ER stress/PKA/GSK-3β/β-catenin pathway as a potential novel strategy for hepatitis C virus-infected patients

BACKGROUND: Chronic hepatitis C virus (HCV) infection causes hepatocellular carcinoma (HCC). The HCC risk, while decreased compared with active HCV infection, persists in HCV-cured patients by direct-acting antiviral agents (DAA). We previously demonstrated that Wnt/β-catenin signaling remained acti...

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Detalles Bibliográficos
Autores principales: Lin, Dong, Chen, Yijia, Koksal, Ali Riza, Dash, Srikanta, Aydin, Yucel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165818/
https://www.ncbi.nlm.nih.gov/pubmed/37158967
http://dx.doi.org/10.1186/s12964-023-01081-9