Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression

BACKGROUND: Bronchial premalignant lesions (PMLs) are composed primarily of cells resembling basal epithelial cells of the airways, which through poorly understood mechanisms have the potential to progress to lung squamous cell carcinoma (LUSC). Despite ongoing efforts that have mapped gene expressi...

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Detalles Bibliográficos
Autores principales: Ning, Boting, Tilston-Lunel, Andrew M., Simonetti, Justice, Hicks-Berthet, Julia, Matschulat, Adeline, Pfefferkorn, Roxana, Spira, Avrum, Edwards, Matthew, Mazzilli, Sarah, Lenburg, Marc E., Beane, Jennifer E., Varelas, Xaralabos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165825/
https://www.ncbi.nlm.nih.gov/pubmed/37150829
http://dx.doi.org/10.1186/s13046-023-02674-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165825/
https://www.ncbi.nlm.nih.gov/pubmed/37150829
http://dx.doi.org/10.1186/s13046-023-02674-5

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