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Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression
BACKGROUND: Bronchial premalignant lesions (PMLs) are composed primarily of cells resembling basal epithelial cells of the airways, which through poorly understood mechanisms have the potential to progress to lung squamous cell carcinoma (LUSC). Despite ongoing efforts that have mapped gene expressi...
Autores principales: | Ning, Boting, Tilston-Lunel, Andrew M., Simonetti, Justice, Hicks-Berthet, Julia, Matschulat, Adeline, Pfefferkorn, Roxana, Spira, Avrum, Edwards, Matthew, Mazzilli, Sarah, Lenburg, Marc E., Beane, Jennifer E., Varelas, Xaralabos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165825/ https://www.ncbi.nlm.nih.gov/pubmed/37150829 http://dx.doi.org/10.1186/s13046-023-02674-5 |
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