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Complement and complement regulatory proteins are upregulated in lungs of COVID-19 patients

We explored the pathological changes and the activation of local complement system in COVID-19 pneumonia. Lung paraffin sections of COVID-19 infected patients were analyzed by HE (hematoxylin-eosin) staining. The deposition of complement C3, the deposition of C3b/iC3b/C3d and C5b-9, and the expressi...

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Detalles Bibliográficos
Autores principales: Ge, Xiaowen, Yu, Zhui, Guo, Xinxin, Li, Ling, Ye, Ling, Ye, Maosong, Yuan, Jingping, Zhu, Chouwen, Hu, Weiguo, Hou, Yingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier GmbH. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165854/
https://www.ncbi.nlm.nih.gov/pubmed/37244049
http://dx.doi.org/10.1016/j.prp.2023.154519